CacoGoblet

24 transwell insert plates seeded with 21 days differentiated and polarized Caco-2 and HT-29 cells with an absorptive and mucus-secreting phenotype, respectively. This co-culture allows evaluating the in vitro intestinal absorption of drug targets at a barrier physiologically closer to the intestinal epithelium. In addition, their responsiveness to inflammatory mediators provides valuable information on the efficacy of anti-inflammatory drugs.